GPR18 Rabbit pAb, HRP conjugated(bs-12015R-HRP)-100ul

GPR18 Rabbit pAb, HRP conjugat

ed(bs-12015R-HRP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-12015R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-12015R-HRP
    英文名称GPR18 Rabbit pAb, HRP conjugated
    中文名称HRP标记的G蛋白偶联受体18抗体
    英文别名G protein coupled receptor 18; G-protein coupled receptor 18GPCRW; GPR 18; GPR18; N arachidonyl glycine receptor; NAGly receptor; GPR18_HUMAN; GPCR18.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human G protein coupled receptor 18
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能G protein coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR18 is a member of this family and has been reported to be expressed at high levels in testis and spleen and at lower levels in other tissues associated with endocrine and immunologic/hematologic functions. It is thought to be a receptor for N arachidonyl glycine. It may contribute to regulation of the immune system.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR18 is a 331 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor family. Expressed abundantly in spleen and testis, GPR18 functions as a receptor for N-arachidonyl glycine and is thought to contribute to the regulation of the immune system. GPR18 activity is mediated by G proteins that specifically inhibit adenylyl cyclase.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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