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- Bioss
- bs-1478R-BF350
- 2025年09月30日
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100ul
| 产品编号 | bs-1478R-BF350 |
| 英文名称 | PAFR/PAF Receptor Rabbit pAb, BF350 conjugated |
| 中文名称 | BF350标记的血小板活化因子受体抗体 |
| 英文别名 | Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1. |
| 产品应用 | Flow-Cyt=1µg/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PAFR |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Blood Cardiovascular > Blood > Platelets Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | Interacts with ARRB1. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1µg/Test} |
| {IF} | {1:100-500} |
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PAFR/PAF Receptor Rabbit pAb, BF350 conjugated(bs-1478R-BF350)-100ul
￥2980
