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- Bioss
- bs-18486R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-18486R-Bio |
| 英文名称 | ZDHHC8 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的锌指蛋白378抗体 |
| 英文别名 | ZDHC8_HUMAN; Palmitoyltransferase ZDHHC8; EC:2.3.1.225; Zinc finger DHHC domain-containing protein 8; DHHC-8; Zinc finger protein 378; KIAA1292; ZDHHCL1; ZNF378; DHHC8; |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ZDHHC8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. |
| 组织特异性 | Widely expressed. |
| 相似性 | Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. |
| 功能 | Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (Probable). Through the palmitoylation of ABCA1 regulates the localization of the transporter to the plasma membrane and thereby regulates its function in cholesterol and phospholipid efflux (Probable). Could also pamitoylate the D(2) dopamine receptor DRD2 and regulate its stability and localization to the plasma membrane (Probable). Could also play a role in glutamatergic transmission. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
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ZDHHC8 Rabbit pAb, Biotin conjugated(bs-18486R-Bio)-100ul
￥2980
