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- Bioss
- bs-12348R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-12348R-Bio |
| 英文名称 | 5T4 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的滋养层细胞糖蛋白5T4抗体 |
| 英文别名 | 5T4; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; M6P1; TPBG; TPBG_HUMAN; Trophoblast glycoprotein. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TPBG/5T4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor immunology > Tumor-associated antigens Developmental Biology > Lineage specification > Ectoderm Developmental Biology > Lineage specification > Endoderm Developmental Biology > Lineage specification > Mesoderm Stem Cells > Lineage Markers > Ectoderm Stem Cells > Lineage Markers > Endoderm Stem Cells > Lineage Markers > Mesoderm |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| 相似性 | Contains 6 LRR (leucine-rich) repeats. _x000D_ Contains 1 LRRCT domain. _x000D_ Contains 1 LRRNT domain. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TPBG is a 420 amino acid single-pass type I membrane protein expressed by all types of trophoblasts as early as 9 weeks of development. TPBG contains an N-terminal putative signal sequence, a 310-residue extracellular region, a membrane anchorage domain and a 44-amino acid cytoplasmic tail with a potential phosphorylation site. The extracellular region has seven potential N-glycosylation sites and seven leucine-rich repeats, which are located in two regions separated by a hydrophilic stretch. Suggested to be involved in cell adhesion, TPBG may also be associated with tumor growth and progression. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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5T4 Rabbit pAb, Biotin conjugated(bs-12348R-Bio)-100ul
￥2980
