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- Bioss
- bs-12007R-BF405
- 2025年09月30日
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100ul
| 产品编号 | bs-12007R-BF405 |
| 英文名称 | GRIK3 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的谷氨酸受体红藻氨酸离子3/谷氨酸受体7抗体 |
| 英文别名 | EAA5; Excitatory amino acid receptor 5; GLR 7; GLR7; GLU R7; GLUR 7; GluR 7a; GluR-7; GLUR7; GluR7a; Glutamate receptor 7; Glutamate receptor; Glutamate receptor ionotropic kainate 3; GRIK 3; GRIK3; GRIK3_HUMAN; ionotropic kainate 3. |
| 产品应用 | Flow-Cyt=2ug/test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GRIK3/GLR7 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > AMPA / Kainate Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > More Channels Neuroscience > Neurotransmitter > Amino Acids > Glutamate |
| 亚基 | Homotetramer, and heterotetramer with either GRIK4 or GRIK5. Interacts with PRKCABP. Interacts with NETO2. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK3 subfamily. |
| 功能 | Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/test} |
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GRIK3 Rabbit pAb, BF405 conjugated(bs-12007R-BF405)-100ul
￥2980
