ENPP1 Rabbit pAb, AP conjugated(bs-22274R-AP)-100ul

ENPP1 Rabbit pAb, AP conjugate

d(bs-22274R-AP)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-22274R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-22274R-AP
    英文名称EN‌‌PP1 Rabbit pAb, AP conjugated
    中文名称AP标记的核苷酸内焦磷酸酶/磷酸二酯酶1抗体
    英文别名Alkaline phosphodiesterase 1; ARHR2; E-N‌‌PP 1; Ectonucleotide pyrophosphatase/phosphodiesterase 1; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; EN‌‌PP1_HUMAN; Ly 41 antigen; M6S1; Membrane component chromosome 6 surface marker 1; N‌‌PP1; N‌‌PPase; N‌‌PPS; Nucleotide pyrophosphatase; PC-1; PCA1; PDNP1; phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma cell membrane glycoprotein 1; Plasma-cell membrane glycoprotein PC-1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse EN‌‌PP1
    亚型IgG
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Types of disease > Diabetes

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    亚基Homodimer; disulfide-linked.
    亚细胞定位Cytoplasmic
    组织特异性Expressed in plasma cells and also in a number of non-lymphoid tissues, including the distal convoluted tubule of the kidney, chondrocytes and epididymis.
    翻译后修饰Autophosphorylated as part of the catalytic cycle of phosphodiesterase/pyrophosphatase activity._x000D_
    N-glycosylated._x000D_
    It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
    相似性Belongs to the peptidase S8 family. Furin subfamily.
    功能Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料EN‌‌PP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.The subtilisin-like Prohormone Convertase (PC) family is a group of cellular enzymes that cleave most prohormones and neuropeptide precursors. Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous ~10 kDa amino-terminal proregion, a highly conserved ~55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ENPP1 Rabbit pAb
    ￥600
    杭州戴格生物技术有限公司
    2025年07月12日询价
    CALML6 多克隆抗体 22274-1-AP
    ￥1350
    Proteintech中国公司
    2025年10月13日询价
    Rabbit Anti-Mouse Enpp1 pAb
    询价
    卡梅德生物科技（天津）有限公司
    2025年07月12日询价
    ENPP1|ENPP1抗体|ENPP1 Antibody, HRP conjugated|多抗
    ￥1980
    武汉华美生物工程有限公司CUSABIO®
    2025年07月13日询价
    AP-2γ (PT1333R) PT™ Rabbit mAb
    询价
    ImmunoWay Biotechnology Company
    2025年10月31日询价
    ENPP1 Rabbit pAb, AP conjugated(bs-22274R-AP)-100ul
    ￥2980