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- Bioss
- bs-7507R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-7507R-HRP |
| 英文名称 | Sprouty 2 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的快速发育生长因子同源蛋白2抗体 |
| 英文别名 | hSPRY 2; hSPRY2; MGC23039; Sprouty homolog 2(Drosophila); Sprouty homolog 2; Sprouty2; Spry 2; Spry2; SPY2_HUMAN. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Sprouty 2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Angiogenic Factors Neuroscience > Neurology process > Neural Signal Transduction Stem Cells > Mesenchymal Stem Cells > Surface Molecules Stem Cells > Signaling Pathways > TGF beta > Cytoplasmic |
| 亚基 | Interacts with RAF1. |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor). |
| 相似性 | Belongs to the sprouty family. _x000D_ Contains 1 SPR (sprouty) domain. |
| 功能 | May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty 2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C terminus of the protein. Significant sequence divergence occurs at the N terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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Sprouty 2 Rabbit pAb, HRP conjugated(bs-7507R-HRP)-100ul
￥2980
