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FOXRED1 Rabbit pAb, Biotin con

jugated(bs-13209R-Bio)-100ul
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  • ¥2980
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  • bs-13209R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-13209R-Bio
    英文名称FOXRED1 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的单跨膜蛋白FOXRED1抗体
    英文别名FAD dependent oxidoreductase domain containing 1; FAD dependent oxidoreductase domain containing protein 1; FAD-dependent oxidoreductase domain-containing protein 1; FOXRED 1; FOXRED1; FP634; FXRD1_HUMAN; H17.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human FOXRED1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Signal Transduction > Metabolism > Mitochondrial

    Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

    亚细胞定位Membrane; Single-pass membrane protein (Potential).
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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