SERPINB1 Rabbit pAb, HRP conjugated(bs-22116R-HRP)-100ul

SERPINB1 Rabbit pAb, HRP conju

gated(bs-22116R-HRP)-100ul
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  • ¥2980
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  • bs-22116R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-22116R-HRP
    英文名称SERPINB1 Rabbit pAb, HRP conjugated
    中文名称HRP标记的丝氨酸蛋白酶抑制剂B1抗体
    英文别名Anti elastase; EI; ELANH2; ILEU_HUMAN; LEI; Leukocyte elastase inhibitor; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; Pi-2; PI2; Serine(or cysteine) proteinase inhibitor clade B(ovalbumin) member 1; Serpin B1; Serpin peptidase inhibitor clade B(ovalbumin) member 1; serpinb1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SERPINB1
    亚型IgG
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cytoplasm.
    相似性Belongs to the serpin family. Ov-serpin subfamily.
    功能Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbumin-related serpins). Human SerpinB1, also designated monocyte/neutrophil elastase inhibitor (M/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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