Galectin 12 Rabbit pAb, APC-Cy5.5 conjugated(bs-8413R-APC-Cy5.5)-100ul

Galectin 12 Rabbit pAb, APC-Cy

5.5 conjugated(bs-8413R-APC-Cy5.5)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-8413R-APC-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-8413R-APC-Cy5.5
    英文名称Galectin 12 Rabbit pAb, APC-Cy5.5 conjugated
    中文名称APC-Cy5.5标记的半乳糖凝集素12抗体
    英文别名Galectin related inhibitor of proliferation; galectin-12; GRIP1; Lectin galactoside binding soluble 12(galectin 12); LEG12_HUMAN.
    产品应用Flow-Cyt=1ug/test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Galectin 12/LGALS12
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Nucleus.
    组织特异性Not widely expressed. Predominantly expressed in adipose tissue.
    相似性Contains 2 galectin domains.
    功能Binds lactose. May participate in the apoptosis of adipocytes.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. Galectin-12 is a member of the galectin family consisting of b-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may participate in the apoptosis of adipocytes. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. Galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipo-cytes and is upregulated when preadipocytes undergo cell cycle arrest, concomitant with acquisition of the competence to undergo differentiation in response to adipogenic hormone stimulation. Galectin-12 is an adipocyte-expressed protein which is downregulated by various insulin resistance-inducing hormones. As a result, galectin-12 may play a role in the pathogenesis of insulin resistance.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/test}
    {IF}{1:100-500}

     

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