Collagen III Rabbit pAb, Cy5.5 conjugated(bs-0948R-Cy5.5)-100ul

Collagen III Rabbit pAb, Cy5.5

conjugated(bs-0948R-Cy5.5)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-0948R-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-0948R-Cy5.5
    英文名称Collagen III Rabbit pAb, Cy5.5 conjugated
    中文名称Cy5.5标记的Ⅲ型胶原蛋白/胶原蛋白3/3型胶原蛋白抗体
    英文别名COL 3A1; COL3A1; Collagen alpha 1(III) chain; Collagen III alpha 1 chain precursor; Collagen III alpha 1 polypeptide; Collagen type III alpha 1(Ehlers Danlos syndrome type IV autosomal dominant); Collagen type III alpha 1; Collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; Type III collagen; CO3A1_HUMAN; Collagen alpha-1(III) chain; Type III collagen; type III preprocollagen alpha 1 chain..
    产品应用Flow-Cyt=1ug/Test, ICC/IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Collagen alpha 1(III) chain
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Collagen

    Stem Cells > Mesenchymal Stem Cells > Chondrogenesis

    Stem Cells > Mesenchymal Stem Cells > Osteogenesis

    亚基Trimers of identical alpha 1(III) chains. The chains are linked to each other by interchain disulfide bonds. Trimers are also cross-linked via hydroxylysines.
    亚细胞定位Secreted, extracellular space, extracellular matrix.
    翻译后修饰Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
    _x000D_ O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group.
    相似性Belongs to the fibrillar collagen family.
    _x000D_ Contains 1 fibrillar collagen NC1 domain.
    _x000D_ Contains 1 VWFC domain.
    功能Collagen type III occurs in most soft connective tissues along with type I collagen.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}
    {ICC/IF}{1:50-200}

     

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