- ￥2980
- Bioss
- bs-13174R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-13174R-AP |
| 英文名称 | FIZ1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的锌指蛋白798抗体 |
| 英文别名 | FLJ00416; FLJ14768; FLT3 interacting zinc finger 1; Flt3 interacting zinc finger protein 1; Zinc finger protein 798; ZNF798; FIZ1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FIZ1/ZNF798 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and PDGFR. Interacts with NRL (By similarity). |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Widely expressed. |
| 相似性 | Contains 11 C2H2-type zinc fingers. |
| 功能 | FIZ1 is a zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. It also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. FIZ1 (FLT3-interacting zinc finger 1), also known as ZNF798 (zinc finger protein 798), is a 496 amino acid zinc-finger protein that contains eleven C2H2-type zinc fingers. Localized to both the cytoplasm and the nucleus and expressed in a wide variety of tissues, FIZ1 is thought to repress the function of Nrl (neural retina leucine zipper) in photoreceptors, possibly regulating the expression of rod-specific genes. Additionally, FIZ1 interacts with the receptor-related tyrosine kinase Flt-3/Flk-2 and, via this interaction, may be involved in the regulation of lymphoid and hematopoietc cells. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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FIZ1 Rabbit pAb, AP conjugated(bs-13174R-AP)-100ul
￥2980
