FOXR2 Rabbit pAb, AP conjugated(bs-16176R-AP)-100ul

FOXR2 Rabbit pAb, AP conjugate

d(bs-16176R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-16176R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-16176R-AP
    英文名称FOXR2 Rabbit pAb, AP conjugated
    中文名称AP标记的叉头蛋白R2抗体
    英文别名Forkhead box protein N6; Forkhead box protein R2; FOXN6; FOXR2_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human FOXR2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXN

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > Other FOXes

    亚细胞定位Nuclear
    组织特异性Expressed in breast cancer cell lines and primary cancer.
    相似性Contains 1 fork-head DNA-binding domain.
    功能Forkhead-box (FOX) transcription factors are implicated in carcinogenesis through gene amplification, retroviral integration, or chromosomal translocation. Human FOXR2 mRNA was expressed in breast cancer cell line and primary breast cancer.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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