DLL4 Rabbit pAb, Biotin conjugated(bs-5909R-Bio)-100ul

DLL4 Rabbit pAb, Biotin conjug

ated(bs-5909R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-5909R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      100ul

    产品编号bs-5909R-Bio
    英文名称DLL4 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的DeltaD抗体
    英文别名deltaD; delta4; delta-like 4(Drosophila); delta-like 4 homolog(Drosophila); Drosophila delta homolog 4; delta-like 4 homolog; delta-like 4 protein; Aei; After eight; dld; DLL4_HUMAN; delta-like protein 4; Drosophila delta homolog 4; delta 4 precursor; delta 4; delta ligand 4; notch ligand delta-2; hdelta2; MGC126344; notch ligand DLL4.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human DLL4
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell differentiation

    Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation

    Neuroscience > Neurology process > Notch Pathway

    亚基Binds to Notch-1 and Notch-4 (By similarity).
    亚细胞定位Membrane; Single-pass type I membrane protein (Probable).
    组织特异性Expressed in vascular endothelium.
    翻译后修饰Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
    相似性Contains 1 DSL domain.
    _x000D_ Contains 8 EGF-like domains.
    功能Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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