DENTT Rabbit pAb, BF350 conjugated(bs-7051R-BF350)-100ul

DENTT Rabbit pAb, BF350 conjug

ated(bs-7051R-BF350)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-7051R-BF350
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-7051R-BF350
    英文名称DENTT Rabbit pAb, BF350 conjugated
    中文名称BF350标记的细胞分裂核仁蛋白1抗体
    英文别名CASK interacting nucleosome assembly protein; CINAP; CDA1; Cell division autoantigen 1 nucleolar protein; CTCL tumor antigen se20-4; DENTT; Differentially-expressed nucleolar TGF-beta1 target protein; Nuclear protein of 79 kDa; TSPY-like 2; TSPY-like protein 2; Tspyl2; Testis-specific Y-encoded-like protein 2; Cutaneous T-cell lymphoma-associated antigen se20-4; SE20 4; SE204; CTCL-associated antigen se20-4; NP79; TSYL2_HUMAN.
    产品应用ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human DENTT
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Growth Factors > TGF

    Immunology > Innate Immunity > Cytokines

    Neuroscience > Neurology process > Neurogenesis

    亚基Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TRB1 and TSPYL2.
    亚细胞定位Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons.
    组织特异性Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
    翻译后修饰Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation (Probable).
    相似性Belongs to the nucleosome assembly protein (NAP) family.
    功能Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CASK interacting nucleosome assembly protein (CINAP) modulates gene expression and its abundance in cultured neurons is regulated by synaptic activity. CINAP is widely expressed in different regions of adult mouse brain, including the cerebral cortex, hippocampus, striatum, hypothalamus, cerebellum, and two adult brain regions known to generate progenitor neurons. During early development, CINAP is also expressed in regions where neuronal progenitor cells are actively dividing, the ventricular and subventricular zones, suggesting that in addition to regulating gene expression in mature neurons CINAP may also play a role in dividing cells.

     

    应用推荐稀释比例
    {ICC/IF}{1:100-500}

     

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