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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-7051R-BF350 |
| 英文名称 | DENTT Rabbit pAb, BF350 conjugated |
| 中文名称 | BF350标记的细胞分裂核仁蛋白1抗体 |
| 英文别名 | CASK interacting nucleosome assembly protein; CINAP; CDA1; Cell division autoantigen 1 nucleolar protein; CTCL tumor antigen se20-4; DENTT; Differentially-expressed nucleolar TGF-beta1 target protein; Nuclear protein of 79 kDa; TSPY-like 2; TSPY-like protein 2; Tspyl2; Testis-specific Y-encoded-like protein 2; Cutaneous T-cell lymphoma-associated antigen se20-4; SE20 4; SE204; CTCL-associated antigen se20-4; NP79; TSYL2_HUMAN. |
| 产品应用 | ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DENTT |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Growth Factors > TGF Immunology > Innate Immunity > Cytokines Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TRB1 and TSPYL2. |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons. |
| 组织特异性 | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. |
| 翻译后修饰 | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation (Probable). |
| 相似性 | Belongs to the nucleosome assembly protein (NAP) family. |
| 功能 | Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CASK interacting nucleosome assembly protein (CINAP) modulates gene expression and its abundance in cultured neurons is regulated by synaptic activity. CINAP is widely expressed in different regions of adult mouse brain, including the cerebral cortex, hippocampus, striatum, hypothalamus, cerebellum, and two adult brain regions known to generate progenitor neurons. During early development, CINAP is also expressed in regions where neuronal progenitor cells are actively dividing, the ventricular and subventricular zones, suggesting that in addition to regulating gene expression in mature neurons CINAP may also play a role in dividing cells. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:100-500} |
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DENTT Rabbit pAb, BF350 conjugated(bs-7051R-BF350)-100ul
¥2980





