- ￥2980
- Bioss
- bs-19736R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-19736R-Bio |
| 英文名称 | RASGRP3 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体 |
| 英文别名 | Calcium and DAG-regulated guanine nucleotide exchange factor III; Grp3; GRP3_HUMAN; Guanine nucleotide exchange factor for Rap1; Kiaa0846; RAS guanyl releasing protein 3(calcium and DAG regulated); RAS guanyl releasing protein 3 calcium and DAG regualated guanine nucleotide exchange factor iii; Ras guanyl-releasing protein 3; RASGRP3. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RASGRP3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family |
| 相似性 | Belongs to the RASGRP family. _x000D_ Contains 2 EF-hand domains. _x000D_ Contains 1 N-terminal Ras-GEF domain. _x000D_ Contains 1 phorbol-ester/DAG-type zinc finger. _x000D_ Contains 1 Ras-GEF domain. |
| 功能 | Guanine nucleotide exchange factor (GEF) for Ras and Rap1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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RASGRP3 Rabbit pAb, Biotin conjugated(bs-19736R-Bio)-100ul
￥2980
