- ￥2980
- Bioss
- bs-8044R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-8044R-AP |
| 英文名称 | KBTBD10 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的BTB-kelch蛋白家族10抗体 |
| 英文别名 | cb52; fb24f05; fc15e07; Gm112; KBTBD10; Kel like protein 23; Kelch related protein 1; KRP1; MGC143407; Sarcosin; sbcb52; wufb24f05; wufc15e07; KBTBA_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KBTBD10 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ub-like Proteins |
| 亚基 | Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10. |
| 亚细胞定位 | Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Note=Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia. |
| 翻译后修饰 | Ubiquitinated and probably targeted for proteasome-independent degradation. |
| 相似性 | Contains 1 BTB (POZ) domain. Contains 5 Kelch repeats. _x000D_ |
| 功能 | Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sarcosin contains 1 BTB (POZ) domain and is required for pseudopod elongation in transformed cells. Sarcosin mRNA is up-regulated by less than two folds in the heart in human patients with HCM. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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KBTBD10 Rabbit pAb, AP conjugated(bs-8044R-AP)-100ul
￥2980
