- ￥2980
- Bioss
- bs-13257R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-13257R-Bio |
| 英文名称 | GABA A receptor pi Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的G氨基丁酸受体pi/GABAA Rπ抗体 |
| 英文别名 | GABA(A) receptor; GABA(A) receptor subunit pi; GABRP; gamma aminobutyric acid(GABA) A receptor pi; gamma aminobutyric acid A receptor pi; gamma aminobutyric acid receptor pi subunit; gamma aminobutyric acid receptor subunit pi; gamma-aminobutyric acid receptor subunit pi; GBRP_HUMAN; MGC126386; MGC126387; GABA A receptor pi. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GABRP/GABA A receptor pi |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > GABA Receptors Neuroscience > Neurotransmitter > Amino Acids > GABA |
| 亚细胞定位 | Cell junction; synapse; postsynaptic cell membrane. Cell membrane. |
| 组织特异性 | Most abundant in the uterus, also expressed in lung, thymus and prostate. |
| 相似性 | Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily. |
| 功能 | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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GABA A receptor pi Rabbit pAb, Biotin conjugated(bs-13257R-Bio)-100ul
￥2980
