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100ul
| 产品编号 | bs-11744R-PerCP |
| 英文名称 | Engrailed 1 Rabbit pAb, PerCP conjugated |
| 中文名称 | PerCP标记的同源盒蛋白转录因子EN1抗体 |
| 英文别名 | EN1/Engrailed 1; Engrailed1; En 1; EN1; EN-1; Engrailed; Engrailed homeobox 1; Engrailed homolog 1; HME1_HUMAN; Homeobox protein en-1; Homeobox protein engrailed 1; Homeobox protein engrailed-1; Homeobox protein engrailed-1; Hu-En-1; Mo-en.1. |
| 产品应用 | Flow-Cyt=1μg/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EN1/Engrailed 1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| 研究领域 | Developmental Biology > Lineage specification > Ectoderm Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Epigenetics and Nuclear Signaling > Transcription > Other factors Neuroscience > Neurology process > Neurogenesis Stem Cells > Lineage Markers > Ectoderm Stem Cells > Signaling Pathways > Hedgehog > Nuclear |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the engrailed homeobox family. _x000D_ Contains 1 homeobox DNA-binding domain. |
| 保存条件 | Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson’s disease. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg/Test} |
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Engrailed 1 Rabbit pAb, PerCP conjugated(bs-11744R-PerCP)-100ul
¥2980





