Engrailed 1 Rabbit pAb, PerCP conjugated(bs-11744R-PerCP)-100ul

Engrailed 1 Rabbit pAb, PerCP

conjugated(bs-11744R-PerCP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11744R-PerCP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-11744R-PerCP
    英文名称Engrailed 1 Rabbit pAb, PerCP conjugated
    中文名称PerCP标记的同源盒蛋白转录因子EN1抗体
    英文别名EN1/Engrailed 1; Engrailed1; En 1; EN1; EN-1; Engrailed; Engrailed homeobox 1; Engrailed homolog 1; HME1_HUMAN; Homeobox protein en-1; Homeobox protein engrailed 1; Homeobox protein engrailed-1; Homeobox protein engrailed-1; Hu-En-1; Mo-en.1.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human EN1/Engrailed 1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300.
    研究领域

    Developmental Biology > Lineage specification > Ectoderm

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Neuroscience > Neurology process > Neurogenesis

    Stem Cells > Lineage Markers > Ectoderm

    Stem Cells > Signaling Pathways > Hedgehog > Nuclear

    亚细胞定位Nucleus.
    相似性Belongs to the engrailed homeobox family.
    _x000D_ Contains 1 homeobox DNA-binding domain.
    保存条件Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson’s disease.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

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