FcRH2 Rabbit pAb, Biotin conjugated(bs-16065R-Bio)-100ul

FcRH2 Rabbit pAb, Biotin conju

gated(bs-16065R-Bio)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-16065R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-16065R-Bio
    英文名称FcRH2 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的CD307b抗体
    英文别名CD307b; Fc receptor homolog 2; Fc receptor like protein 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; FCRL 2; FcRL2; FCRL2_HUMAN; IFGP family protein 4; IFGP4; Immunoglobulin receptor translocation associated 4 protein; Immunoglobulin receptor translocation-associated protein 4; IRTA4; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human FcRH2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Adaptive Immunity > B Cells > Non-CD

    Immunology > Immunoglobulins > Receptors

    亚细胞定位Cell membrane.
    组织特异性Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).
    翻译后修饰Isoform 2 is N- and O-glycosylated, and phosphorylated.
    相似性Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
    功能May have an regulatory role in normal and neoplastic B cell development.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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