ADAM28 Rabbit pAb, Biotin conjugated(bs-22523R-Bio)-100ul

ADAM28 Rabbit pAb, Biotin conj

ugated(bs-22523R-Bio)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-22523R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-22523R-Bio
    英文名称ADAM28 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的去整合素样金属蛋白酶28抗体
    英文别名A disintegrin and metalloproteinase domain 28; ADAM28; ADAM 28; ADAM-28; MDC L; Metalloproteinase like disintegrin like and cysteine rich protein L; eMDCII; MDC-Ls; TECADAM; ADA28_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ADAM28
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > ECM > Extracellular matrix > ADAM protein family

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > ADAMs

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > ADAM Protein Family

    亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein.
    Isoform 2: Secreted.
    组织特异性Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.
    相似性Contains 1 disintegrin domain.
    Contains 1 EGF-like domain.
    Contains 1 peptidase M12B domain.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ADAM28 was first described in lymphocytes, also in Thymic Endothelial Cells (TECADAM), as well as in the epididymus. Later works describe two forms of ADAM28: ADAM28-S and ADAM28-L (short and long forms). The short form is a soluble, alternatively spliced form lacking the transmembrane and cytoplasmic domains. Message levels of the short form were found to be much lower than the long form in the tissues studied, but these may be tissue-specific differences. In humans, ADAM28 is reported in lymphocytes by some authors and to be absent from mature lymphocytes by others. The thyroid, lung, trachea, esophagus, and stomach have been shown to express human ADAM28 message. Knockout mice lacking B cells and T cells express ADAM28 message in the thyroid, lung, trachea, esophagus, and stomach. A member of the metalloproteinase family containing disintegrin-like domains (ADAMs) the functions of ADAM28 are still poorly understood. ADAM28 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active. Other ADAMs family members (ADAM10, ADAM17) have been more thoroughly studied and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions. The full length ADAM28 (ADAM28 Long) sequence codes for a 775 amino acid protein with a predicted mass is 87.2 kDa, and a pI of 6.50. The soluble ADAM28 (ADAM-28 Short) is a 540 amino acid sequence, with a predicted mass of 61.3 kDa, and a pI of 6.58. Other forms of ADAM28 have been reported with slightly different carboxyterminal regions.ADAM28 may play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. It may be involved in sperm maturation. There are 2 isoforms of ADAM28: one short secreted and one long membrane bound.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ADAM28 Rabbit pAb
    ￥1990
    上海圻明生物科技有限公司
    2025年07月12日询价
    Rabbit Anti-Human ADAM28 pAb
    询价
    卡梅德生物科技（天津）有限公司
    2025年06月06日询价
    Insulin Receptor R Polyclonal Antibody Biotin Conjugated[C92606Bio]
    询价
    南京赛戈巍生物科技有限公司
    2025年09月22日询价
    ADAM28 Rabbit Polyclonal Antibody
    ￥500
    北京百奥创新科技有限公司
    2025年03月17日询价
    SARS-CoV-2 N Rabbit pAb(bs-41417R)-100ug
    ￥2500
    北京博奥森生物技术有限公司
    2025年10月16日询价
    ADAM28 Rabbit pAb, Biotin conjugated(bs-22523R-Bio)-100ul
    ￥2980