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- bs-13055R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-13055R-AP |
| 英文名称 | EEF1D Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的延伸因子EF-1δ抗体 |
| 英文别名 | Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EEF1D |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNAs Epigenetics and Nuclear Signaling > Transcription > Other factors Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚基 | EF-1 is composed of 4 subunits: alpha, beta, deltaisoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2. |
| 亚细胞定位 | Isoform 2: Nucleus. |
| 组织特异性 | Isoform 2 is specifically expressed in brain,cerebellum and testis. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the EF-1-beta/EF-1-delta family. |
| 功能 | EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a subunit of the elongation factor-1complex, which is responsible for the enzymatic delivery ofaminoacyl tRNAs to the ribosome. This subunit, delta, functions asguanine nucleotide exchange factor. It is reported that followingHIV-1 infection, this subunit interacts with HIV-1 Tat. Thisinteraction results in repression of translation of host cellproteins and enhanced translation of viral proteins. Severalalternatively spliced transcript variants encoding multipleisoforms have been found for this gene. Related pseudogenes havebeen defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided byRefSeq, Aug 2010]. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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EEF1D Rabbit pAb, AP conjugated(bs-13055R-AP)-100ul
￥2980
