HLA-C Mouse mAb, Cy5.5 conjugated(bsm-43093M-Cy5.5)-100ul

HLA-C Mouse mAb, Cy5.5 conjuga

ted(bsm-43093M-Cy5.5)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bsm-43093M-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bsm-43093M-Cy5.5
    英文名称HLA-C Mouse mAb, Cy5.5 conjugated
    中文名称Cy5.5标记的组织相容性蛋白1单克隆抗体
    英文别名HLA-C; Major Histocompatibility Complex, Class I; HLA Class I Histocompatibility Antigen, C alpha Chain; HLA-JY3; D6S204; PSORS1; HLAC; Major Histocompatibility Antigen HLA-C; MHC Class I Antigen Heavy Chain HLA-C; Human Leukocyte Antigen-C alpha Chain; Psoriasis Susceptibility 1; Human Leukocyte Antigen C; HLA-C Antigen; HLA-Cw; HLC-C; MHC; HLAC_HUMAN.
    产品应用Flow-Cyt=1ug/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Mouse
    免疫原Recombinant human HLA-C protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Monoclonal
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Adaptive Immunity > MHC > Class I

    Microbiology > Interspecies Interaction > Host Virus Interaction

    亚基Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein. Interacts with HTLV-1 p12I accessory protein.
    亚细胞定位Cell Membrane; Type I membrane protein.
    翻译后修饰N-linked glycosylation at Asn-110 is required for efficient interaction with CANX and CALR chaperones and appropriate HLA-C-B2M folded conformers prior to peptide loading
    相似性Belongs to the MHC class I family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
    功能HLA-C (Major Histocompatibility Complex, Class I, C) is a Protein Coding gene. Diseases associated with HLA-C include Psoriasis 1 and H‌‌uman immunodeficiency virus Type 1. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and TAP binding. An important paralog of this gene is HLA-B.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. About 6000 HLA-C alleles have been described. The HLA system plays an important role in the occurrence and outcome of infectious diseases, including those caused by the malaria parasite, the H‌‌uman immunodeficiency virus (HIV), and the S‌‌evere acute respiratory syndrome coronavirus (SARS-CoV). The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population.[provided by RefSeq, Aug 2020]

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}
    {IF}{1:100-500}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    human CD3 Mouse mAb, Cy5 conjugated(bsm-30092M-Cy5)-25T/50T/100T
    ￥680
    北京博奥森生物技术有限公司
    2025年09月30日询价
    HLA-C Mouse mAb[63733]
    询价
    南京赛戈巍生物科技有限公司
    2025年09月22日询价
    Anti-NF-M/Cy5
    ￥220
    上海信裕生物科技有限公司
    2025年07月11日询价
    Anti-NF-M/Cy5
    ￥220
    上海再康生物科技有限公司
    2025年11月20日询价
    HLA-C|HLA-C抗体|HLA-C Antibody, HRP conjugated|多抗
    ￥1980
    武汉华美生物工程有限公司CUSABIO®
    2025年07月15日询价
    HLA-C Mouse mAb, Cy5.5 conjugated(bsm-43093M-Cy5.5)-100ul
    ￥2980