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- bs-3463R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-3463R-AP |
| 英文名称 | phospho-TH (Ser31) Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的磷酸化酪氨酸羟化酶抗体 |
| 英文别名 | Tyrosine Hydroxylase(phospho-Ser31); Dystonia 14; DYT14; DYT5b; EC 1.14.16.2; OTTHUMP00000011225; OTTHUMP00000011226; ple; Protein Pale; TH; The; TY3H_RAT; TYH; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthesised phosphopeptide derived from rat TH around the phosphorylation site of Ser31 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Cancer > Cancer Metabolism > Response to hypoxia Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Neuroscience > Cell Type Marker > Neuron marker > Soma marker Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine Neuroscience > Neurotransmitter > Biogenic Amines > Noradrenaline |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Mainly expressed in the brain and adrenal glands. |
| 组织特异性 | Mainly expressed in the brain and adrenal glands. |
| 翻译后修饰 | In vitro, phosphorylation of Ser-19 increases the rate of Ser-40 phosphorylation, which results in enzyme opening and activation. |
| 相似性 | Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. |
| 功能 | Plays an important role in the physiology of adrenergic neurons. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | bs-0016P is one synthetic peptide derived from human TH. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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phospho-TH (Ser31) Rabbit pAb, AP conjugated(bs-3463R-AP)-100ul
￥2980
