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- Bioss
- bs-20272R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-20272R-Bio |
| 英文名称 | ADCY3 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的腺苷酸环化酶3抗体 |
| 英文别名 | A cyclase III; AC3; adenylate cyclase 3; Adenylate cyclase type III; ADCY3_HUMAN; Adenylate cyclase type 3; ATP pyrophosphate-lyase 3; AC-III; Adenylate cyclase, olfactive type; AC3. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ADCY3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Metabolism > Types of disease > Cancer Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. |
| 相似性 | Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. |
| 功能 | Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones, neurotransmitters and other regulatory molecules. cAMP, in subsequent steps down the signal transduction pathway, can stimulate cAMP-dependent protein kinase A (cPKA), and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways, gene expression, and affect memory functions etc. The stimulation of adenylate cyclases starts with interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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ADCY3 Rabbit pAb, Biotin conjugated(bs-20272R-Bio)-100ul
￥2980
