TRPV5 Rabbit pAb, BF350 conjugated(bs-8534R-BF350)-100ul

TRPV5 Rabbit pAb, BF350 conjug

ated(bs-8534R-BF350)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-8534R-BF350
  • 2025年09月30日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-8534R-BF350
    英文名称TRPV5 Rabbit pAb, BF350 conjugated
    中文名称BF350标记的辣椒素受体5抗体
    英文别名Calcium transport protein 2; Calcium transporter 2; CAT 2; CAT2; ECAC 1; ECaC; ECAC1; Epithelial calcium channel 1; Osm 9 like TRP channel 3; Osm-9-like TRP channel 3; OTRPC 3; OTRPC3; Transient receptor potential cation channel subfamily V member 5; TRPV 5; TrpV5; TRPV5_HUMAN.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TRPV5
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚基Homotetramer and probably heterotetramer with TRPV6. Interacts with TRPV6. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with calmodulin. Interacts with BSPRY, which results in its inactivation (By similarity).
    亚细胞定位Apical cell membrane. Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3.
    组织特异性Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.
    翻译后修饰Glycosylated.
    相似性Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
    Contains 5 ANK repeats.
    功能Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, the thermal-sensitive, capsaicin-insensitive TRPV3 is expressed at warm temperatures; expression increases in response to noxious temperatures. Human TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain. In addition, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1. TRPV3 associates with VR-1 and may modulate VR-1 activity. The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, multiple potential phosphorylation sites, an N-linked glycosylation site and three ankyrin repeat regions. It is abundantly expressed in kidney, jejunum and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum. TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine; the 5’-flanking region of TRPV5 contains four putative vitamin D3-responsive elements.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ZN350 rabbit pAb
    ￥900
    上海贝博生物科技有限公司
    2025年07月11日询价
    ZN350 rabbit pAb
    询价
    ImmunoWay Biotechnology Company
    2025年07月11日询价
    ZN350 rabbit pAb
    ￥1260
    杭州臻优品生物科技有限公司
    2025年07月05日询价
    ZN350 rabbit pAb
    询价
    武汉佰瑞得生物技术有限公司
    2025年07月10日询价
    Frizzled 10/CD350 Rabbit pAb
    询价
    上海圻明生物科技有限公司
    2025年07月10日询价
    TRPV5 Rabbit pAb, BF350 conjugated(bs-8534R-BF350)-100ul
    ￥2980