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- Bioss
- bs-7674R-Cy3
- 2025年09月30日
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100ul
| 产品编号 | bs-7674R-Cy3 |
| 英文名称 | Porimin Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的前细胞胀亡受体诱导膜损伤蛋白抗体 |
| 英文别名 | KCT3; Keratinocytes associated transmembrane protein 3; Pro oncosis receptor inducing membrane injury; Serine/threonine rich receptor; TMEM123; Transmembrane protein 123; PORIM_HUMAN. |
| 产品应用 | Flow-Cyt=2ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Porimin |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. |
| 相似性 | Belongs to the CD164 family. |
| 功能 | Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
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Porimin Rabbit pAb, Cy3 conjugated(bs-7674R-Cy3)-100ul
￥2980
