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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-19821R-Cy7 |
| 英文名称 | SLC32A1 Rabbit pAb, Cy7 conjugated |
| 中文名称 | Cy7标记的溶质载体家族蛋白32成员A1抗体 |
| 英文别名 | bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; Slc32a1; solute carrier family 32(GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SLC30A9 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cytoplasmic vesicle membrane; Multi-pass membrane protein |
| 组织特异性 | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| 相似性 | Belongs to the amino acid/polyamine transporter 2 family._x000D_ |
| 功能 | Involved in the uptake of GABA and glycine into the synaptic vesicles. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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SLC32A1 Rabbit pAb, Cy7 conjugated(bs-19821R-Cy7)-100ul
¥2980





