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- bs-9554R-FITC
- 2025年09月30日
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100ul
| 产品编号 | bs-9554R-FITC |
| 英文名称 | GTPBP9 Rabbit pAb, FITC conjugated |
| 中文名称 | FITC标记的鸟嘌呤核苷酸结合蛋白9抗体 |
| 英文别名 | DNA damage-regulated overexpressed in cancer 45 protein; DOC45; GBP45; GTP-binding protein 9(putative); GTP-binding protein 9; GTP-binding protein PTD004; homologous yeast-44.2 protein; Obg like ATPase 1; Obg-like ATPase 1; OLA1; OLA1_HUMAN; PTD004. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GTPBP9 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Signal Transduction > Second Messenger > Nucleotide Messenger > GTP |
| 亚基 | Monomer. _x000D_ |
| 亚细胞定位 | Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm. |
| 组织特异性 | Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus. |
| 相似性 | Belongs to the GTP1/OBG family. Contains 1 G (guanine nucleotide-binding) domain. _x000D_ |
| 功能 | Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GTP-binding protein 9 is a 396 amino acid protein that belongs to the Obg-related GTPase family under the translation factors (TRAFAC) class. Originally thought to only have GTPase activity, Obg-related GTPase family members have been shown to also have ATPase activity. In Homo sapians, GTPBP9 exhibits a preference for binding ATP over GTP, with GTP binding occuring only at high nucleotide concentration. One cause for ATP affinity and GTP discrimination is thought to be a substitution of glutamine for a hydrophobic amino acid in Obg-related family members; this is the same substitution that inactivates Ras-like GTPases. GTPBP9 contains a C-terminal TGS domain that binds to ligands and an N-terminal G domain which binds nucleotides. GTPBP9 is expressed as three isoforms produced by alternative splicing. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
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GTPBP9 Rabbit pAb, FITC conjugated(bs-9554R-FITC)-100ul
￥2980
