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- Bioss
- bs-10029R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-10029R-HRP |
| 英文名称 | Nectin 4 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的脊髓灰质炎病毒受体相关蛋白4抗体 |
| 英文别名 | Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4; DKFZp686K05193; EDSS1; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; pvrl4; PVRL4_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Nectin 4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction. Processed poliovirus receptor-related protein 4: Secreted. |
| 组织特异性 | Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. |
| 相似性 | Belongs to the nectin family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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Nectin 4 Rabbit pAb, HRP conjugated(bs-10029R-HRP)-100ul
￥2980
