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- bs-5739R-AP
- 2026年10月14日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-5739R-AP |
| 英文名称 | Cyclin A1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的周期素A1蛋白抗体 |
| 英文别名 | CCN A1; Cyclin-A1; CCNA 1; CCNA1; CyclinA1; MGC132235; MGC159139. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cyclin A1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Cyclins > Cyclin A family Cell Biology > Cell Cycle > Cyclins > Cyclin A Family Epigenetics and Nuclear Signaling > Cell cycle > Cyclins > Cyclin A Family |
| 亚细胞定位 | Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER. |
| 相似性 | Belongs to the cyclin family. Cyclin AB subfamily. |
| 功能 | Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A1 is expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. It binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Cyclin A1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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CCNA1 | Cyclin-A1 Rabbit pAb, AP conj.(bs-5739R-AP)-100ul
￥2980
