NCAM2 Rabbit pAb, PE-Cy5.5 conj.(bs-11094R-PE-Cy5.5)-100ul产品图

NCAM2 Rabbit pAb, PE-Cy5.5 con

j.(bs-11094R-PE-Cy5.5)-100ul
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  • ￥2980
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  • bs-11094R-PE-Cy5.5
  • 2026年10月14日
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    北京博奥森生物技术有限公司
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      100ul

    产品编号bs-11094R-PE-Cy5.5
    英文名称NCAM2 Rabbit pAb, PE-Cy5.5 conjugated
    中文名称PE-Cy5.5标记的神经细胞粘附分子2抗体
    英文别名N CAM 2; N CAM 21; N CAM2; N CAM21; N-CAM-2; NCAM 2; NCAM 21; NCAM-2; Ncam2; NCAM2_HUMAN; NCAM21; Neural cell adhesion molecule 2; OCAM GPI; R4B12; RB 8 neural cell adhesion molecule; RB8 neural cell adhesion molecule; RNCAM.
    产品应用Flow-Cyt=3ug/test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human NCAM2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Neuroscience > Neurology process > Neural Signal Transduction

    Neuroscience > Sensory System > Olfactory system

    亚基Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    亚细胞定位Cell membrane.
    组织特异性Expressed most strongly in adult and fetal brain.
    相似性Contains 2 fibronectin type-III domains.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    功能May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line; this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.

     

    应用推荐稀释比例
    {Flow-Cyt}{3ug/test}

     

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