TH | Tyrosine Hydroxylase Rabbit pAb, PE conj.(bs-0016R-PE)-100ul产品图

TH | Tyrosine Hydroxylase Rabb

it pAb, PE conj.(bs-0016R-PE)-100ul
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  • bs-0016R-PE
  • 2026年10月14日
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    北京博奥森生物技术有限公司
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      100ul

    产品编号bs-0016R-PE
    英文名称Tyrosine Hydroxylase Rabbit pAb, PE conjugated
    中文名称PE标记的酪氨酸羟化酶抗体
    英文别名DYT14; DYT5b; ple; Protein Pale; c; The; TYH; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyk2; TY3H_HUMAN; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TH
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis

    Cancer > Cancer Metabolism > Response to hypoxia

    Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    Neuroscience > Cell Type Marker > Neuron marker > Soma marker

    Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine

    Neuroscience > Neurotransmitter > Biogenic Amines > Noradrenaline

    亚基Homotetramer.
    亚细胞定位Mainly expressed in the brain and adrenal glands.
    组织特异性Mainly expressed in the brain and adrenal glands.
    翻译后修饰In vitro, phosphorylation of Ser-19 increases the rate of Ser-40 phosphorylation, which results in enzyme opening and activation.
    相似性Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    功能Plays an important role in the physiology of adrenergic neurons.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料bs-0016P is one synthetic peptide derived from human TH. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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