SLAMF7 Rabbit pAb, HRP conjugated(bs-2544R-HRP)-100ul

SLAMF7 Rabbit pAb, HRP conjuga

ted(bs-2544R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-2544R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-2544R-HRP
    英文名称SLAMF7 Rabbit pAb, HRP conjugated
    中文名称HRP标记的SLAMF7抗体
    英文别名19A; 19A24 protein; CD2 like receptor activating cytotoxic cells; CD2 subset 1; CD 319; CD319; CD319 antigen; CRACC; CS1; Membrane protein FOAP 12; Novel Ly9; Novel LY9(lymphocyte antigen 9) like protein; Protein 19A; SLAM family member 7; SLAMF 7; SLAMF7.
    产品应用ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLAMF7
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Innate Immunity > NK Cells

    亚基Isoform 1 binds to SH2D1A when its cytoplasmic tail is phosphorylated in the presence of FYN (in vitro).
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. Isoform 3 is expressed at much lower level than isoform 1
    相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    功能Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion._x000D_
    Isoform 3 does not mediate any NK cell activation.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

     

    应用推荐稀释比例
    {ELISA}{1:5000-10000}

     

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