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CALCRL Rabbit pAb, AP conjugat

ed(bs-21475R-AP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-21475R-AP
  • 2026年01月20日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-21475R-AP
    英文名称CALCRL Rabbit pAb, AP conjugated
    中文名称AP标记的降钙素基因相关肽1型受体抗体
    英文别名CGRPR; CRLR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CGRP type 1 receptor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; Calcitonin Receptor Like Receptor; CGRP type 1 receptor; CALRL_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CALCRL
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > Calcium Signaling

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚基Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Predominantly expressed in the lung and heart.
    相似性Belongs to the G-protein coupled receptor 2 family.
    功能Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料bs-1860P is one synthetic peptide derived from human CGRPR1.CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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    图标文献和实验
    相关实验
    • Western 杂交

      SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts.    ・        

    • Developing Genetically Engineered Mouse Models to Study Tumor Suppression

      Literature Cited    Armstrong, J.F., Kaufman, M.H., Harrison, D.J., and Clarke, A.R. 1995. High‐frequency developmental abnormalities in p53‐deficient mice. Curr

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