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- Bioss
- bs-4940R-AP
- 2025年11月02日
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100ul
| 产品编号 | bs-4940R-AP |
| 英文名称 | Metallothionein 3 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的金属硫蛋白3抗体 |
| 英文别名 | Mt3; Mt-3; Mt 3; GIFB; GRIF; Metallothionein III; GIF; Growth inhibitory factor; Metallothionein3; Metallothionein-3; Metallothionein-III; MT-III; MT III; MT3_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Metallothionein 3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Cellular metabolic process Cancer > Cancer Metabolism > Response to hypoxia Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Neuroscience > Neurology process > Growth and Development > Neurotrophins |
| 组织特异性 | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. |
| 相似性 | Belongs to the metallothionein superfamily. Type 1 family. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MT3, Metallothionein 3, binds heavy metals. It contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. MT3 inhibits survival and neurite formation of cortical neurons in vitro. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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文献和实验Developing Genetically Engineered Mouse Models to Study Tumor Suppression
Brinster, R.L., Chen, H.Y., Warren, R., Sarthy, A., and Palmiter, R.D. 1982. Regulation of metallothionein‐thymidine kinase fusion plasmids injected into mouse eggs. Nature 296:39‐42.
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