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- 技术资料
- 规格:
500ug
| 产品编号 | bs-19554P |
| 英文名称 | NXF3 Antibody Blocking Peptide |
| 中文名称 | 核RNA输出因子3封闭多肽 |
| 英文别名 | Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. |
| 组织特异性 | Expressed at high level in testis and at low level in a small number of tissues. |
| 相似性 | Belongs to the NXF family. Contains 1 NTF2 domain. Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | May function as a tissue-specific nuclear mRNA export factor. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008] |
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