ARRDC1 多克隆抗体  21030-1-AP

ARRDC1 多克隆抗体 21030-1-AP

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  • ¥1350 - 3000
  • Proteintech已认证
  • 21030-1-AP
  • 2025年10月09日
  • WB, IHC, ELISA
  • Rabbit
  • human, mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human ARRDC1 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse

    • 宿主

      Rabbit

    • 应用范围

      WB, IHC, ELISA

    • 靶点

      ARRDC1

    • 抗体英文名

      ARRDC1 Polyclonal antibody

    • 抗体名

      ARRDC1 Polyclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1350.0
    规格:100ul产品价格:¥2200.0
    规格:150ul产品价格:¥3000.0

    经过测试的应用

    Positive WB detected inHEK-293 cells, HEK-293 exosomes, human plasma, human plasma exosomes
    Positive IHC detected inmouse kidney tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:500-1:1000
    Immunohistochemistry (IHC)IHC : 1:50-1:500
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    21030-1-AP targets ARRDC1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

    经测试应用 WB, IHC, ELISA
    经测试反应性 human, mouse
    免疫原

    CatNo: Ag15341

    Product name: Recombinant human ARRDC1 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 84-433 aa of BC032346

    Sequence: HSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVRTIAEVEGAGVKAWRRAQWHEQILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTPES

    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 arrestin domain containing 1
    别名 Alpha-arrestin 1, arrestin domain containing 1, Arrestin domain-containing protein 1
    计算分子量 433 aa, 46 kDa
    观测分子量46-50 kDa
    GenBank蛋白编号BC032346
    基因名称 ARRDC1
    Gene ID (NCBI) 92714
    RRIDAB_3085633
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDQ8N5I2
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    ARRDC1, or Arrestin-Domain Containing Protein 1, is a protein that plays a significant role in the formation and release of extracellular vesicles, specifically a subtype known as ARMMs (Arrestin-Domain Containing Protein 1-mediated microvesicles). ARRDC1 is localized to the cytosolic side of the plasma membrane and recruits the ESCRT-I complex protein TSG101 to initiate outward membrane budding. This protein is also involved in the regulation of protein cargo and release of extracellular vesicles, including both exosomes and ectosomes. The absence of ARRDC1 can lead to changes in the protein cargo within these vesicles, indicating its importance in the sorting and packaging process.

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