- ￥960 - 2390
- Proteintech
- APC-65074
- 2025年10月09日
- FC (Intra)
- Rat
- mouse
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- 详细信息
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
APC Fluorescent Dye
- 适应物种：
mouse
- 宿主：
Rat
- 应用范围：
FC (Intra)
- 靶点：
IL-4
- 抗体英文名：
APC Anti-Mouse IL-4 (11B11)
- 抗体名：
APC Anti-Mouse IL-4 (11B11)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2390.0 |
经过测试的应用
| Positive FC (Intra) detected in | PMA and ionomycin stimulated mouse Th2-polarized splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65074 targets IL-4 in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 4 |
| 别名 | 11B11, Il 4, Il4, interleukin 4 |
| GenBank蛋白编号 | BC027514 |
| 基因名称 | IL-4 |
| Gene ID (NCBI) | 16189 |
| RRID | AB_2935216 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P07750 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)
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