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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, mouse
- 宿主:
Rabbit
- 应用范围:
WB, ELISA
- 靶点:
Phospho-Cardiac Troponin I (Ser23/24)
- 抗体英文名:
Phospho-Cardiac Troponin I (Ser23/24) Polyclonal antibody
- 抗体名:
Phospho-Cardiac Troponin I (Ser23/24) Polyclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2480.0 |
| 规格: | 150ul | 产品价格: | ¥3280.0 |
经过测试的应用
| Positive WB detected in | mouse heart tissue, λ phosphatase treated mouse heart tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
30937-1-AP targets Phospho-Cardiac Troponin I (Ser23/24) in WB, ELISA applications and shows reactivity with Human, mouse samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | Human, mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | troponin I type 3 (cardiac) |
| 别名 | Cardiac troponin I, CMD2A, CMH7, cTnI, Phospho-Cardiac Troponin I (Ser23/24), RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle |
| 计算分子量 | 210 aa, 24 kDa |
| 观测分子量 | 26 kDa |
| GenBank蛋白编号 | BC096165 |
| 基因名称 | Cardiac Troponin I |
| Gene ID (NCBI) | 7137 |
| RRID | AB_3669787 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P19429 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Cardiac Troponin I (cTnI) is produced by cardiac muscle. To date, most investigative effort in phosphorylation mediated regulation of cTnI function has focused on the actions of PKA and PKC. Evidence from studies in a variety of systems, ranging from reconstituted myofilament proteins to cultured myocytes or transgenic animals with heterologous expression of modified cTnI proteins, indicates that PKA-mediated functional effects (eg, decreased myofilament Ca2 sensitivity) are mediated principally through the phosphorylation of Ser22/23 (equivalent to Ser23/24, including the initiating Met, in the rodent sequence) within the unique N-terminal extension of cTnI. (PMID: 15514163)
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