- ￥2800
- Proteintech
- PE-66692
- 2025年10月09日
- IF-P
- Mouse
- human, mouse, rat, pig
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human ASGR1 protein
- 亚型：
IgG1
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
PE Fluorescent Dye
- 适应物种：
human, mouse, rat, pig
- 宿主：
Mouse
- 应用范围：
IF-P
- 靶点：
ASGR1
- 抗体英文名：
PE-conjugated ASGR1 Monoclonal antibody
- 抗体名：
PE-conjugated ASGR1 Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF-P detected in | rat liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
PE-66692 targets ASGR1 in IF-P applications and shows reactivity with human, mouse, rat, pig samples.
| 经测试应用 | IF-P |
| 经测试反应性 | human, mouse, rat, pig |
| 免疫原 |
CatNo: Ag2310 Product name: Recombinant human ASGR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-291 aa of BC032130 Sequence: MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | asialoglycoprotein receptor 1 |
| 别名 | asialoglycoprotein receptor 1, HL-1, Asgpr1, ASGP-R 1, ASGPR 1 |
| 计算分子量 | 291 aa, 33 kDa |
| 观测分子量 | 42-46 kDa |
| GenBank蛋白编号 | BC032130 |
| 基因名称 | ASGR1 |
| Gene ID (NCBI) | 432 |
| RRID | AB_3674012 |
| 偶联类型 | PE Fluorescent Dye |
| 最大激发/发射波长 | 496 nm, 565 nm / 578 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P07306 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.
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