- ￥5800
- Proteintech
- 83840-7-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Rabbit
- human, mouse, rat
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- 详细信息
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- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 宿主：
Rabbit
- 应用范围：
WB, Indirect ELISA
- 靶点：
Phospho-PKC Alpha (Ser657)
- 抗体英文名：
Phospho-PKC Alpha (Ser657) Recombinant monoclonal antibody, PBS Only
- 抗体名：
Phospho-PKC Alpha (Ser657) Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
83840-7-PBS targets Phospho-PKC Alpha (Ser657) in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | protein kinase C, alpha |
| 别名 | p PKC α (Ser 657), Phospho PKC Alpha, Phospho-PKC Alpha, Phospho-PKC Alpha(Ser657), Phospho-PKC Alpha-Ser657 |
| 计算分子量 | 77 kDa |
| 观测分子量 | 77 kDa |
| GenBank蛋白编号 | AK055431 |
| 基因名称 | PKC Alpha |
| Gene ID (NCBI) | 5578 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P17252 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PKCs are a family of serine/threonine kinases involved in various processes in cells including proliferation, differentiation, cell survival, and apoptosis. PKC family is composed of three different subgroups: conventional (cPKC), the novel (nPKC) and atypical (aPKC). PKCα, β1, β2, and γ belong to cPKC, PKCδ, ε, η and θ are nPKC, whereas aPKC comprises of PKCζ and λ/ι. All PKCs consist of the N-terminal regulatory region and C-terminal catalytic region (kinase domain). PKCs are physiologically activated by various extracellular signals transduced by hormones, growth factors, cytokines or antigens. The presence of activated PKCs on internal membranes leads to the phosphorylation of various interacting proteins. (PMID: 32466765, PMID: 12417016)
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