- ￥5800
- Proteintech
- 67649-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Mouse
- human, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human GNE protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, rat
- 宿主：
Mouse
- 应用范围：
WB, Indirect ELISA
- 靶点：
GNE
- 抗体英文名：
GNE Monoclonal antibody, PBS Only
- 抗体名：
GNE Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
67649-1-PBS targets GNE in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag18702 Product name: Recombinant human GNE protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 376-722 aa of BC121179 Sequence: SIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| 别名 | 2A11E10, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, GLCNE, hydrolyzing, IBM2 |
| 计算分子量 | 722 aa, 79 kDa |
| 观测分子量 | 79 kDa |
| GenBank蛋白编号 | BC121179 |
| 基因名称 | GNE |
| Gene ID (NCBI) | 10020 |
| RRID | AB_2882849 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q9Y223 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.
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