- ￥5800
- Proteintech
- 82787-3-PBS
- 2025年10月09日
- WB, Cytometric bead array, Indirect ELISA
- Rabbit
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human CNR1 protein
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 宿主：
Rabbit
- 应用范围：
WB, Cytometric bead array, Indirect ELISA
- 靶点：
Cannabinoid receptor 1
- 抗体英文名：
Cannabinoid receptor 1 Recombinant monoclonal antibody, PBS Only (Detector)
- 抗体名：
Cannabinoid receptor 1 Recombinant monoclonal antibody, PBS Only (Detector)
- 规格：
100ug
产品信息
82787-3-PBS targets Cannabinoid receptor 1 as part of a matched antibody pair:
MP02192-2: 82787-5-PBS capture and 82787-3-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | WB, Cytometric bead array, Indirect ELISA |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag12625 Product name: Recombinant human CNR1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-121 aa of BC074812 Sequence: MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAV |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | cannabinoid receptor 1 (brain) |
| 别名 | CNR1, CANN6, cannabinoid receptor 1 (brain), CB R, CB1 |
| 计算分子量 | 472 aa, 53 kDa |
| 观测分子量 | 60 kDa |
| GenBank蛋白编号 | BC074812 |
| 基因名称 | Cannabinoid receptor 1 |
| Gene ID (NCBI) | 1268 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P21554 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.
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文献和实验would be the approx. 25 kDa Receptor-binding domain (RBD) of SARS-CoV-23 , which is the best-suited antigen for CoViD-19 immunity testing4. The most common reason is a simple steric hindrance that blocks access of antibodies from the specimen to the capture
细胞在肿瘤、病毒、细菌、寄生虫、移植组织、过敏原、甚至自身抗原的适应性免疫应答中都发挥着重要的调节作用。大部分 T 淋巴细胞在其细胞表面表达单一的、高度特异性的抗原受体（TCR），与 MHC-抗原肽复合物相结合并识别其中特异的抗原肽，启动获得性/特异性免疫应答机制，比如 T 细胞介导的细胞免疫和 B 细胞介导的体液免疫。由于 TCR 与 MHC-抗原肽复合物之间的亲和力低，半衰期短，相互结合后容易快速脱落，重组的可溶性 MHC-抗原肽复合物单体并不适合用于抗原特异性的 T 细胞检测。1996
Size‐Exclusion Chromatography with On‐Line Light Scattering
.6.6 Chromatograms of E. coli SCF. CHO SCF contains >30% carbohydrate and thus the three‐detector method was used. 100 µl of 3.8 mg/ml of E. coli SCF was injected into a Superdex 200 column (Pharmacia) with PBS as eluent at a flow rate of 0.5 ml/min. The solid line
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