- ￥5800
- Proteintech
- 66198-1-PBS
- 2025年10月09日
- IHC, IF-P, Indirect ELISA
- Mouse
- human, mouse, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human Insulin protein
- 亚型：
IgG2a
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 宿主：
Mouse
- 应用范围：
IHC, IF-P, Indirect ELISA
- 靶点：
INS
- 抗体英文名：
INS Monoclonal antibody, PBS Only
- 抗体名：
INS Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66198-1-PBS targets INS in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IHC, IF-P, Indirect ELISA |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag8630 Product name: Recombinant human Insulin protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-110 aa of BC005255 Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | INS |
| 别名 | insulin, 4B6A7 |
| 计算分子量 | 110 aa, 12 kDa |
| GenBank蛋白编号 | BC005255 |
| 基因名称 | INS |
| Gene ID (NCBI) | 3630 |
| RRID | AB_2881591 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P01308 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. INS is synthesized as a precursor molecule, pro-INS, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form.
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