- ￥920 - 2310
- Proteintech
- CL647-65180
- 2025年10月09日
- FC
- Mouse
- Rat
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- 详细信息
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite® Plus 647 Fluorescent Dye
- 适应物种：
Rat
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
CD8a
- 抗体英文名：
CoraLite® Plus 647 Anti-Rat CD8a (OX-8)
- 抗体名：
CoraLite® Plus 647 Anti-Rat CD8a (OX-8)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥920.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2310.0 |
经过测试的应用
| Positive FC detected in | Wistar rat splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL647-65180 targets CD8a in FC applications and shows reactivity with Rat samples.
| 经测试应用 | FC |
| 经测试反应性 | Rat |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD8a molecule |
| 别名 | Cd8a, CD8a molecule |
| GenBank蛋白编号 | BC088126 |
| 基因名称 | Cd8a |
| Gene ID (NCBI) | 24930 |
| RRID | AB_2935000 |
| 偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
| 最大激发/发射波长 | 654 nm / 674 nm |
| 形式 | Liquid |
| 纯化方式 | Purified by protein-A affinity chromatography |
| UNIPROT ID | P07725 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells , on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).
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