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- 详细信息
- 技术资料
- 免疫原:
Recombinant human SCNN1G protein
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
human, pig
- 宿主:
Rabbit
- 应用范围:
WB, ELISA
- 靶点:
SCNN1G
- 抗体英文名:
SCNN1G Polyclonal antibody
- 抗体名:
SCNN1G Polyclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2200.0 |
| 规格: | 150ul | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive WB detected in | A431 cells, COLO 320 cells, PC-3 cells, pig kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
30037-1-AP targets SCNN1G in WB, ELISA applications and shows reactivity with human, pig samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | human, pig |
| 免疫原 |
CatNo: Ag32176 Product name: Recombinant human SCNN1G protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 87-215 aa of BC059391 Sequence: VHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDCA |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | sodium channel, nonvoltage-gated 1, gamma |
| 别名 | Gamma-ENaC, Gamma NaCH, Gamma ENaC, ENaCgamma, ENaCg |
| 计算分子量 | 74 kDa |
| 观测分子量 | 74 kDa |
| GenBank蛋白编号 | BC059391 |
| 基因名称 | SCNN1G |
| Gene ID (NCBI) | 6340 |
| RRID | AB_3669702 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P51170 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SCNN1G (sodium channel, non-voltage-gated 1, gamma), also known as ENaC gamma (epithelial Na(+) channel subunit gamma) or amiloride-sensitive sodium channel subunit gamma, is the gamma subunit of the epithelial Na(+) channel (ENaC). ENaC is expressed in the apical membrane of salt-absorbing epithelia of the kidney, distal colon, and lung. ENaC is a non-voltage gated, constitutively active channel highly selective for sodium. It has an essential role in salt and fluid homeostasis across epithelial tissues. Mutations in the gene of SCNN1G have been associated with Liddle syndrome. Native SCNN1G has a calculated molecular weight of 74 kDa and may undergo post-transcriptional modifications, including glycosylation and proteolytic cleavage (PMID: 12871941; 18086683).
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