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- 详细信息
- 技术资料
- 免疫原:
Recombinant human GRP75 protein
- 亚型:
IgG2a
- 保存条件:
Store at -80°C.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
human, mouse, rat
- 宿主:
Mouse
- 应用范围:
WB, IHC, Indirect ELISA
- 靶点:
GRP75
- 抗体英文名:
GRP75 Monoclonal antibody, PBS Only
- 抗体名:
GRP75 Monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
67563-1-PBS targets GRP75 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, IHC, Indirect ELISA |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag7125 Product name: Recombinant human GRP75 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 331-679 aa of BC000478 Sequence: YLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | heat shock 70kDa protein 9 (mortalin) |
| 别名 | HSPA9, 2B12F2, 75 kDa glucose-regulated protein, CSA, GRP-75 |
| 计算分子量 | 74 kDa |
| 观测分子量 | 75 kDa |
| GenBank蛋白编号 | BC000478 |
| 基因名称 | GRP75 |
| Gene ID (NCBI) | 3313 |
| RRID | AB_2882777 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P38646 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GRP75 (also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA (HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson's disease. (PMID: 21640711, 22920904)
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