- ￥3200
- Proteintech
- CL488-19700
- 2025年10月09日
- IF-P
- Rabbit
- human
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- 详细信息
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- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
CoraLite® Plus 488 Fluorescent Dye
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
IF-P
- 靶点：
LRP2-Specific
- 抗体英文名：
CoraLite® Plus 488-conjugated LRP2-Specific Polyclonal antibody
- 抗体名：
CoraLite® Plus 488-conjugated LRP2-Specific Polyclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF-P detected in | mouse kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-19700 targets LRP2-Specific in IF-P applications and shows reactivity with human samples.
| 经测试应用 | IF-P |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | low density lipoprotein-related protein 2 |
| 别名 | LRP2, LRP 2, Low-density lipoprotein receptor-related protein 2, gp330, Glycoprotein 330 |
| 计算分子量 | 522 kDa |
| 观测分子量 | 280 kDa |
| GenBank蛋白编号 | NM_004525 |
| 基因名称 | LRP2 |
| Gene ID (NCBI) | 4036 |
| RRID | AB_3672707 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P98164 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS). This antibody is specific to LRP2 and detects endogenous LRP2 with an apparent molecular weight 280 kDa, which is smaller than the predicted molecular weight (522 kDa) and probably represent a proteolytic fragment of the large glycoprotein (PMID: 16638803; 8483924).
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文献和实验Site‐Specific Protein Labeling with SNAP‐Tags
conjugated species‐specific secondary antibodies (Invitrogen or Li‐COR, http://www.licor.com) NeutrAvidin, DyLight 800 conjugate (Thermo Scientific
on Veeco DI SPMLab software. 5. Photographs The photographs, showing difference in intensity of Alexa488 signal on glass, SIF, and SACS, were taken with Canon 300D® digital SLR camera. The illumination source was Ti: Sapphire laser (Mai Tai
表达系统（178-541aa）：CSB-EP745804 ENL1 多克隆抗体货号（兔多抗）： No conjugated：CSB-PA745804LA01ENL HRP conjugated：CSB-PA745804LB01ENL FITC conjugated：CSB-PA745804LC01ENL Biotin conjugated：CSB-PA745804LD01ENL 参考文献： [1] Systems Genomics
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