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- 详细信息
- 技术资料
- 免疫原:
Recombinant human KRT5 protein
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
human, mouse
- 宿主:
Rabbit
- 应用范围:
WB, IHC, IF/ICC, IF-P, ELISA
- 靶点:
Pan-Keratin
- 抗体英文名:
Pan-Keratin Polyclonal antibody, PBS Only
- 抗体名:
Pan-Keratin Polyclonal antibody, PBS Only
- 规格:
100ug
产品信息
26411-1-PBS targets Pan-Keratin in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, IF-P, ELISA |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag24184 Product name: Recombinant human KRT5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 316-491 aa of BC024292 Sequence: THVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNI |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | keratin 5 |
| 别名 | pan-CK, CK 5, CK-5, Cytokeratin 5, keratin 5 |
| 计算分子量 | 590 aa, 62 kDa |
| 观测分子量 | 46-58 kDa |
| GenBank蛋白编号 | BC024292 |
| 基因名称 | Cytokeratin 5 |
| Gene ID (NCBI) | 3852 |
| RRID | AB_2880505 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P13647 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Pan-keratin, also known as pan-cytokeratin, refers to a group of antibodies that recognize a broad array of keratin proteins. Keratins are a large family of intermediate filament (IF) proteins that provide structural integrity to epithelial cells. These proteins are essential for maintaining cell shape, strength, and resilience . The keratin gene family is divided into two major groups: type I keratins (acidic) and type II keratins (basic), with 27 type I and 26 type II keratin genes in humans. Pan-keratin immunostaining is widely used in pathology and research due to its ability to detect a variety of keratin proteins, making it a valuable tool for identifying epithelial cells and tissues. This staining technique is particularly useful in the diagnosis of tumors, as it can help distinguish between epithelial and non-epithelial neoplasms. This antibody is a pan-keratin antibody.
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